Genetic Changes in Mammalian Cells Reminiscent of an SOS Response

Overview

Journal Hum Genet

Specialty Genetics

Date 1984 Jan 1

PMID 6092260

Citations 8

Authors

P Herrlich

U Mallick

H Ponta

H J Rahmsdorf

Affiliations

Soon will be listed here.

Abstract

Prior to the isolation of mammalian DNA repair genes and identification of their gene products, the comparison between the bacterial SOS response and various similar reactions in mammalian cells remains rather speculative. The increasing number of observed phenomena including enhanced DNA repair, virus induction, induced cellular differentiation, and neoplastic transformation, all following DNA damage or arrest of replication, are, however, suggestive of an SOS-like system of growth control and may form an entry into this fascinating area.

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References

Sarasin A, Benoit A . Induction of an error-prone mode of DNA repair in UV-irradiated monkey kidney cells. Mutat Res. 1980; 70(1):71-81. DOI: 10.1016/0027-5107(80)90059-7. View

Sarasin A, HANAWALT P . Carcinogens enhance survival of UV-irradiated simian virus 40 in treated monkey kidney cells: induction of a recovery pathway?. Proc Natl Acad Sci U S A. 1978; 75(1):346-50. PMC: 411245. DOI: 10.1073/pnas.75.1.346. View

Sukumar S, Notario V, Barbacid M . Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations. Nature. 1983; 306(5944):658-61. DOI: 10.1038/306658a0. View

Day 3rd R, Ziolkowski C . UV-induced reversion of adenovirus 5ts2 infecting human cells. Photochem Photobiol. 1981; 34(3):403-6. DOI: 10.1111/j.1751-1097.1981.tb09015.x. View

Fridman W, GRESSER I, Bandu M, Aguet M, Neauport-Sautes C . Interferon enhances the expression of Fc gamma receptors. J Immunol. 1980; 124(5):2436-41. View

WITKIN E . Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli. Bacteriol Rev. 1976; 40(4):869-907. PMC: 413988. DOI: 10.1128/br.40.4.869-907.1976. View

Kogoma T, Lark K . Characterization of the replication of Escherichia coli DNA in the absence of protein synthesis: stable DNA replication. J Mol Biol. 1975; 94(2):243-56. DOI: 10.1016/0022-2836(75)90081-9. View

Farzaneh F, Zalin R, Brill D, Shall S . DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation. Nature. 1982; 300(5890):362-6. DOI: 10.1038/300362a0. View

Weimann B . Induction of immunoglobulin synthesis in Abelson murine leukemia virus-transformed mouse lymphoma cells in culture. Cold Spring Harb Symp Quant Biol. 1977; 41 Pt 1:163-4. DOI: 10.1101/sqb.1977.041.01.021. View

10.

Wielckens K, Bredehorst R, Adamietz P, Hilz H . Mono ADP-ribosylation and poly ADP-ribosylation of proteins in normal and malignant tissues. Adv Enzyme Regul. 1982; 20:23-37. DOI: 10.1016/0065-2571(82)90006-1. View

11.

Sonenshein G, Brawerman G . Regulation of immunoglobulin synthesis in mouse myeloma cells. Biochemistry. 1976; 15(25):5497-501. DOI: 10.1021/bi00670a012. View

12.

Jeeves W, Rainbow A . Gamma-ray enhanced reactivation of gamma-irradiated adenovirus in human cells. Biochem Biophys Res Commun. 1979; 90(2):567-74. DOI: 10.1016/0006-291x(79)91273-7. View

13.

Warren S, Schultz R, Chang C, Wade M, Trosko J . Elevated spontaneous mutation rate in Bloom syndrome fibroblasts. Proc Natl Acad Sci U S A. 1981; 78(5):3133-7. PMC: 319514. DOI: 10.1073/pnas.78.5.3133. View

14.

Emerit I, Cerutti P . Clastogenic activity from Bloom syndrome fibroblast cultures. Proc Natl Acad Sci U S A. 1981; 78(3):1868-72. PMC: 319236. DOI: 10.1073/pnas.78.3.1868. View

15.

Little J, Mount D . The SOS regulatory system of Escherichia coli. Cell. 1982; 29(1):11-22. DOI: 10.1016/0092-8674(82)90085-x. View

16.

Schorpp M, Mallick U, Rahmsdorf H, Herrlich P . UV-induced extracellular factor from human fibroblasts communicates the UV response to nonirradiated cells. Cell. 1984; 37(3):861-8. DOI: 10.1016/0092-8674(84)90421-5. View

17.

Lawrence C, CHRISTENSEN R . The mechanism of untargeted mutagenesis in UV-irradiated yeast. Mol Gen Genet. 1982; 186(1):1-9. DOI: 10.1007/BF00422904. View

18.

Lytle C, Goddard J . UV-enhanced virus reactivation in mammalian cells: effects of metabolic inhibitors. Photochem Photobiol. 1979; 29(5):959-62. DOI: 10.1111/j.1751-1097.1979.tb07798.x. View

19.

Mallick U, Rahmsdorf H, Yamamoto N, Ponta H, Wegner R, Herrlich P . 12-O-tetradecanoylphorbol 13-acetate-inducible proteins are synthesized at an increased rate in Bloom syndrome fibroblasts. Proc Natl Acad Sci U S A. 1982; 79(24):7886-90. PMC: 347454. DOI: 10.1073/pnas.79.24.7886. View

20.

Nomura S, Oishi M . Indirect induction of erythroid differentiation in mouse Friend cells: evidence for two intracellular reactions involved in the differentiation. Proc Natl Acad Sci U S A. 1983; 80(1):210-4. PMC: 393341. DOI: 10.1073/pnas.80.1.210. View