Stability of Rat Skin Collagen During Recovery from Under-nutrition

Overview

Journal Biochem J

Specialty Biochemistry

Date 1977 Dec 15

PMID 606256

Authors

D J Etherington

Affiliations

Soon will be listed here.

Abstract

The growth of young rats was arrested for 6 weeks from 48 h after receiving an injection of L-[5-3H]proline. The 3H in the hydroxyproline of the newly synthesized skin collagen remained steady during under-nutrition and did not decrease during the subsequent recovery period. It was concluded that in this animal model the renewed growth did not induce degradation of the pre-existing collagen fibres.

References

Grant R . ESTIMATION OF HYDROXYPROLINE BY THE AUTOANALYSER. J Clin Pathol. 1964; 17:685-6. PMC: 480859. DOI: 10.1136/jcp.17.6.685. View

Messer M . Interference by amino acids and peptides with the photometric estimation of proline. Anal Biochem. 1961; 2:353-9. DOI: 10.1016/0003-2697(61)90008-2. View

Moore S, STEIN W . Procedures for the chromatographic determination of amino acids on four per cent cross-linked sulfonated polystyrene resins. J Biol Chem. 1954; 211(2):893-906. View

McAnulty P, Williams J . Polyamines and their biosynthetic decarboxylases in various tissues of the young rat during recovery from undernutrition. Biochem J. 1977; 162(1):109-21. PMC: 1164574. DOI: 10.1042/bj1620109. View

Klein L, Chandrarajan J . Collagen degradation in rat skin but not in intestine during rapid growth: effect on collagen types I and III from skin. Proc Natl Acad Sci U S A. 1977; 74(4):1436-9. PMC: 430787. DOI: 10.1073/pnas.74.4.1436. View

Kawamoto T, Nagai Y . Developmental changes in glycosaminoglycans, collagen and collagenase activity in embryonic chick skin. Biochim Biophys Acta. 1976; 437(1):190-9. DOI: 10.1016/0304-4165(76)90360-3. View

Bailey A, Robins S, Balian G . Biological significance of the intermolecular crosslinks of collagen. Nature. 1974; 251(5471):105-9. DOI: 10.1038/251105a0. View

Palmer R, McIntosh A, Pusztai A . The nutrition evaluation of kidney beans (Phaseolus vulgaris). The effect of nutritional value of seed germination and changes in trypsin inhibitor content. J Sci Food Agric. 1973; 24(8):937-44. DOI: 10.1002/jsfa.2740240811. View

Dickerson J, Hughes P, McAnulty P . The growth and development of rats given a low-protein diet. Br J Nutr. 1972; 27(3):527-36. DOI: 10.1079/bjn19720122. View

10.

Mailman M, Dresden M . Collagen metabolism in the regenerating forelimb of Notophthalmus viridescens: synthesis, accumulation, and maturation. Dev Biol. 1976; 50(2):378-94. DOI: 10.1016/0012-1606(76)90159-7. View

11.

Dickerson J, McAnulty P . The response of hind-limb muscles of the weanling rat to undernutrition and subsequent rehabilitation. Br J Nutr. 1975; 33(2):171-80. DOI: 10.1079/bjn19750022. View

12.

Ohuchi K, Tsurufuji S . Degradation and turnover of collagen in the mouse skin and the effect of whole body x-irradiation. Biochim Biophys Acta. 1970; 208(3):475-81. DOI: 10.1016/0304-4165(70)90221-7. View

13.

Kennedy J . Liquid scintillation counting medium for aqueous samples. Experientia. 1969; 25(10):1120. DOI: 10.1007/BF01901473. View