Fatigue of Long Duration in Human Skeletal Muscle After Exercise

Overview

Journal J Physiol

Specialty Physiology

Date 1977 Nov 1

PMID 592214

Citations 172

Authors

R H EDWARDS

D K Hill

D A Jones

P A MERTON

Affiliations

Soon will be listed here.

Abstract

1. After severe muscular contraction in man recovery of force is largely complete in a few minutes, but is not wholly so for many hours. The long-lasting element of fatigue is found to occur primarily for low frequencies of stimulation (e.g. 20/sec), and is much less pronounced, or absent, at high frequencies (80/sec). The twitch force is an unreliable measure of the state of fatigue. 2. The long-lasting element of fatigue is not due to depletion of high-energy phosphate nor is it due to failure of electrical activity as recorded from surface electrodes. It is probably the result of an impairment of the process of excitation-contraction coupling. Its practical importance for man could be significant as an explanation of the subjective feelings of weakness following exercise.

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