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Simultaneous Free and Bound Radioactive Vitamin B-12 Urinary Excretion Test

Overview
Journal J Clin Pathol
Specialty Pathology
Date 1965 Sep 1
PMID 5835443
Citations 11
Authors
T K BELL
J M Bridges
M G NELSON
Affiliations
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Abstract

The absorption of vitamin B(12) following the simultaneous administration of (58)Co B(12) and a complex of (57)Co B(12) with human gastric juice was assessed by measurement of urinary excretion of radioactivity. Sixteen control subjects, 13 patients with pernicious anaemia, and four who had had total gastrectomy were studied. The method proved a reliable means of detecting those with intrinsic factor deficiency.

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References
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Kay A . Effect of large doses of histamine on gastric secretion of HCI; an augmented histamine test. Br Med J. 1953; 2(4827):77-80. PMC: 2028464. DOI: 10.1136/bmj.2.4827.77. View