Protein Synthesis by Ribosomes from Heart Muscle: Effect of Insulin and Diabetes

Overview

Journal Science

Specialty Science

Date 1965 Sep 3

PMID 5826524

Citations 13

Authors

O R Rampersad

I G Wool

Affiliations

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Abstract

Incorporation of phenylalanine into protein by ribosomes from the heart muscle of rats is decreased when the ribosomes are from alloxan-diabetic animals. Protein synthesis is increased when the ribosomes are obtained from nondiabetic animals I hour after treatment with insulin. The change due to insulin appears to be an alteration in the function of the ribosome.

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