Some Physiological Properties of Identified Mammalian Neuroglial Cells

Overview

Journal J Physiol

Specialty Physiology

Date 1969 Jul 1

PMID 5821876

Citations 18

Authors

M J Dennis

H M GERSCHENFELD

Affiliations

Soon will be listed here.

Abstract

Mammalian glial cells were identified and studied in the optic nerves of anaesthetized rats. Cells with membrane potentials of 77-85 mV were located in the optic nerve with capillary micropipettes. These were shown to be neuroglia by iontophoretic injection of a fluorescent dye through the recording electrode, followed by histological verification of the location of the dye. No distinction was made between astroglia and oligodendroglia. Neuroglial cells gave no impulse activity. Their membrane potential was studied in isolated optic nerves by varying the ionic composition of the bathing fluid. The glial membrane potential depends predominantly on a transmembrane gradient of potassium ions.

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