Feedback Inhibition of Lysine Biosynthesis in Yeast
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The pathway for the biosynthesis of lysine is feedback-inhibited by lysine in growing yeast.
Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism.
Olin-Sandoval V, Yu J, Miller-Fleming L, Alam M, Kamrad S, Correia-Melo C Nature. 2019; 572(7768):249-253.
PMID: 31367038 PMC: 6774798. DOI: 10.1038/s41586-019-1442-6.
Ford R, Bhattacharjee J Curr Genet. 1995; 28(2):131-7.
PMID: 8590464 DOI: 10.1007/BF00315779.
Inhibition and repression of homocitrate synthase by lysine in Penicillium chrysogenum.
Luengo J, Revilla G, Lopez M, VILLANUEVA J, Martin J J Bacteriol. 1980; 144(3):869-76.
PMID: 6777369 PMC: 294747. DOI: 10.1128/jb.144.3.869-876.1980.
Effect of hydroxylysine on the biosynthesis of lysine in saccharomyces.
Sinha A, Kurtz M, Bhattacharjee J J Bacteriol. 1971; 108(2):715-9.
PMID: 5128332 PMC: 247130. DOI: 10.1128/jb.108.2.715-719.1971.