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Comparison of the Effects of Water Deprivation and Sodium Chloride Imbibition on the Hormone Content of the Neurohypophysis of the Rat

Overview
Journal J Physiol
Specialty Physiology
Date 1969 Aug 1
PMID 5796472
Citations 43
Authors
C W Jones
B T PICKERING
Affiliations
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Abstract

1. Vasopressin and oxytocin have been measured in the neurohypophysis of rats which had either been given a 2% (w/v) NaCl solution to drink or been deprived of drinking water for up to 5 days.2. There was a progressive decrease in the vasopressin content of the glands in both groups; the rates of depletion were not significantly different.3. Oxytocin also decreased progressively in both groups but the glands from the ;saline-treated' rats contained less hormone than those from the ;water-deprived' animals.4. The differences in gland content of oxytocin could not be correlated with differences between the plasma osmolalities or sodium concentrations of the two groups.

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