Indole(ethyl)amine N-methyltransferase in the Brain

Overview

Journal Science

Specialty Science

Date 1969 Aug 1

PMID 5793241

Citations 7

Authors

M Morgan

A J Mandell

Affiliations

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Abstract

An enzyme which N-methylates various indole(ethyl)amine substrates was isolated from brain, separated from the pituitary and the pineal glands. It appeared localized in the supernatant and synaptosomal areas after discontinuous sucrose-gradient ultracentrifugation. This is the first demonstration of the enzyme in brain.

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