Place of Azathioprine for Crohn's Disease
Overview
Authors
Affiliations
The clinical effects of azathioprine have been compared with those of corticosteroids in a group of 112 patients who have come under the care of a single unit between 1963 and 1975. There is no clear evidence that azathioprine alters the course of the disease in the long term; it is of value in obtaining a remission, particularly when the disease affects the large intestine.
Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease.
Chande N, Townsend C, Parker C, MacDonald J Cochrane Database Syst Rev. 2016; 10:CD000545.
PMID: 27783843 PMC: 6464152. DOI: 10.1002/14651858.CD000545.pub5.
Alexander-Williams J, Buchmann P World J Surg. 1980; 4(2):203-8.
PMID: 7405258 DOI: 10.1007/BF02393577.
Azathioprine and 6-mercaptopurine have a role in the treatment of Crohn's disease.
Lennard-Jones J Dig Dis Sci. 1981; 26(4):364-8.
PMID: 7016483 DOI: 10.1007/BF01308381.
Azathioprine has a very limited role in the treatment of Crohn's disease.
SINGLETON J Dig Dis Sci. 1981; 26(4):368-71.
PMID: 6113105 DOI: 10.1007/BF01308382.
Management of perianal Crohn's disease.
Allan A, Keighley M World J Surg. 1988; 12(2):198-202.
PMID: 3293326 DOI: 10.1007/BF01658054.