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Gastric Ulceration Occurring During Indomethacin Therapy

Overview
Journal Br Med J
Specialty General Medicine
Date 1968 Dec 21
PMID 5723725
Citations 15
Authors
R T Taylor
E C Huskisson
G H Whitehouse
F D Hart
D H Trapnell
Affiliations
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Abstract

Dyspeptic symptoms, gastrointestinal bleeding, or the development of anaemia without dyspepsia in patients treated with indomethacin may be manifestations of peptic ulceration. Such manifestations occur with suppositories as well as with capsules. The ulcers in the present series tended to be prepyloric, and often aroused the suspicion of malignancy. Symptoms were promptly relieved and radiological healing occurred rapidly after withdrawal of the drug.

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Gastroparesis Worsens Indomethacin-Induced Gastric Antral Ulcers by Bile Reflux via Activation of 5-HT and Dopamine D Receptors in Mice.

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Indomethacin in rheumatoid arthritis: comparison of oral and rectal dosing.

Baber N, Sibeon R, Laws E, Halliday L, Orme M, Littler T Br J Clin Pharmacol. 1980; 10(4):387-92.

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Suture line ulceration: a complication of gastric partitioning.

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