An Indication of Possible Impending Toxicity During Moderately High Dose Methotrexate Infusions

Overview

Journal Br J Clin Pharmacol

Specialty Pharmacology

Date 1978 Dec 1

PMID 569491

Authors

J W Paxton

E J Stephens

H F WOOD

Affiliations

Soon will be listed here.

References

Turman S, Coleman M, Silver R, Pasmantier M . High dose methotrexate with citrovorum factor in adult resistant lymphoma. Cancer. 1977; 40(6):2823-8. DOI: 10.1002/1097-0142(197712)40:6<2823::aid-cncr2820400612>3.0.co;2-2. View

Djerassi I, Kim J, Nayak N, Ohanissian H, Adler S, Hsieh S . New "rescue" with massive doses of citrovorum factor for potentially lethal methotrexate toxicity. Cancer Treat Rep. 1977; 61(4):749-50. View

Pinedo H, Chabner B . Role of drug concentration, duration of exposure, and endogenous metabolites in determining methotrexate cytotoxicity. Cancer Treat Rep. 1977; 61(4):709-15. View

Rosen G, Ghavimi F, Nirenberg A, Mosende C, Mehta B . High-dose methotrexate with citrovorum factor rescue for the treatment of central nervous system tumors in children. Cancer Treat Rep. 1977; 61(4):681-90. View

Salasoo S, Irving M, FREEDMAN A . Methotrexate megadosage followed by folate rescue. I. A study in clearance patterns. Med J Aust. 1976; 1(21):777-9. View