Absorption of Vitamin E in Children with Biliary Obstruction

Overview

Journal Gut

Specialty Gastroenterology

Date 1971 Jul 1

PMID 5559146

Citations 7

Authors

J T HARRIES

D P Muller

Affiliations

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Abstract

Serum vitamin E levels and red cell haemolysis were measured in 17 children with biliary obstruction after oral and intramuscular loading tests, and during long-term oral administration of differing doses of a fat-soluble and water-miscible preparation of alpha-tocopheryl acetate. The results suggested a severe defect in the intestinal absorption of both preparations. In three of the children who were studied during periods of improving biliary obstruction, absorption was shown to have improved. Bile plays a major role in the absorption of vitamin E from the intestinal tract and the exact mechanism of its action requires further elucidation.

Citing Articles

The relative importance of the factors involved in the absorption of vitamin E in children.

Muller D, HARRIES J, Lloyd J Gut. 1974; 15(12):966-71.

PMID: 4448411 PMC: 1413066. DOI: 10.1136/gut.15.12.966.

A study of the relationship between neurological function and serum vitamin E concentrations in patients with cystic fibrosis.

Willison H, Muller D, Matthews S, Jones S, Kriss A, Stead R J Neurol Neurosurg Psychiatry. 1985; 48(11):1097-102.

PMID: 4078574 PMC: 1028567. DOI: 10.1136/jnnp.48.11.1097.

The role of vitamin E in the treatment of the neurological features of abetalipoproteinaemia and other disorders of fat absorption.

Muller D, Lloyd J, Wolff O J Inherit Metab Dis. 1985; 8 Suppl 1:88-92.

PMID: 3930848 DOI: 10.1007/BF01800666.

Effect of abnormal liver function on vitamin E status and supplementation in adults with cystic fibrosis.

Stead R, Muller D, Matthews S, Hodson M, Batten J Gut. 1986; 27(6):714-8.

PMID: 3721295 PMC: 1433330. DOI: 10.1136/gut.27.6.714.

Vitamin E--its role in neurological function.

Muller D Postgrad Med J. 1986; 62(724):107-12.

PMID: 3540925 PMC: 2418603. DOI: 10.1136/pgmj.62.724.107.

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