A Combined Qualitative and Quantitative Procedure for the Chemical Analysis of Urinary Calculi

Overview

Journal J Clin Pathol

Specialty Pathology

Date 1971 Mar 1

PMID 5551382

Citations 10

Authors

A Hodgkinson

Affiliations

Soon will be listed here.

Abstract

A better understanding of the physico-chemical principles underlying the formation of calculus has led to a need for more precise information on the chemical composition of stones. A combined qualitative and quantitative procedure for the chemical analysis of urinary calculi which is suitable for routine use is presented. The procedure involves five simple qualitative tests followed by the quantitative determination of calcium, magnesium, inorganic phosphate, and oxalate. These data are used to calculate the composition of the stone in terms of calcium oxalate, apatite, and magnesium ammonium phosphate. Analytical results and derived values for five representative types of calculi are presented.

Citing Articles

Effects of Composite Probiotic Food on Urinary, Serum Biochemical and Oxidative Stress Parameters in a Urolithiatic Rat Model.

Sreeja V, Suman D, Vahora N, Prajapati J Food Technol Biotechnol. 2024; 62(3):397-407.

PMID: 39497692 PMC: 11531678. DOI: 10.17113/ftb.62.03.24.8372.

A 13 year hospital based study on the Trend of Urinary Stone Disease in Uttarakhand, India.

Kakkar M, Kakkar R Nepal J Epidemiol. 2021; 11(1):949-958.

PMID: 33868741 PMC: 8033642. DOI: 10.3126/nje.v11i1.35896.

Laser-induced breakdown spectroscopy is a reliable method for urinary stone analysis.

Mutlu N, Ciftci S, Gulecen T, Oztoprak B, Demir A Turk J Urol. 2016; 42(1):21-6.

PMID: 27011877 PMC: 4791077. DOI: 10.5152/tud.2016.76402.

Laparoendoscopic single-site pyelolithotomy with use of a carter-thomason needle grasper.

Seo I, Rim J Korean J Urol. 2013; 54(3):163-7.

PMID: 23526200 PMC: 3604568. DOI: 10.4111/kju.2013.54.3.163.

The establishment of a standard and real patient kidney stone library utilizing Fourier transform-infrared spectroscopy with a diamond ATR accessory.

Mulready K, McGoldrick D Urol Res. 2012; 40(5):483-98.

PMID: 22246314 DOI: 10.1007/s00240-011-0456-9.

References

Rosenthal A, Yaseen A . Improved qualitative screening test for cystinuria and homocystinuria. Clin Chim Acta. 1969; 26(2):363-4. DOI: 10.1016/0009-8981(69)90393-3. View

Pak C . Physicochemical basis for formation of renal stones of calcium phosphate origin: calculation of the degree of saturation of urine with respect to brushite. J Clin Invest. 1969; 48(10):1914-22. PMC: 322428. DOI: 10.1172/JCI106158. View

Freeman J, BEELER M . Kidney stone analysis. Postgrad Med. 1969; 46(5):51-6. DOI: 10.1080/00325481.1969.11697297. View

Robertson W, Peacock M, Nordin B . Activity products in stone-forming and non-stone-forming urine. Clin Sci. 1968; 34(3):579-94. View

HOLT P, TARNOKY A . The analysis of calculi using microchemical methods. J Clin Pathol. 1953; 6(2):114-7. PMC: 1023566. DOI: 10.1136/jcp.6.2.114. View

Finlayson B, MILLER Jr G . Urine ion equilibria. A numerical approach demonstrated by application to antistone therapy. Invest Urol. 1969; 6(4):428-40. View

Pollack S, Carlson G . A comparison of x-ray diffraction and infrared technics for identifying kidney stones. Am J Clin Pathol. 1969; 52(6):656-60. DOI: 10.1093/ajcp/52.6.656. View

Schneider H . [The anorganic content of kidney calculi and its effect on the type of calculi]. Urologe. 1968; 7(6):347-52. View

LEONARD R, BUTT A . Quantitative identification of urinary calculi. Clin Chem. 1955; 1(4):241-8. View

10.

McIntosh J, Salter R . THE QUALITATIVE EXAMINATION OF URINARY CALCULI. J Clin Invest. 1942; 21(6):751-4. PMC: 435191. DOI: 10.1172/JCI101351. View

11.

Dawson J, Heaton F . The determination of magnesium in biological materials by atomic absorption spectrophotometry. Biochem J. 1961; 80:99-106. PMC: 1243957. DOI: 10.1042/bj0800099. View

12.

Thind S, Nath R . Chemical analysis of urinary calculi in Chandigarh area. Indian J Med Res. 1969; 57(9):1790-801. View

13.

Hodgkinson A, Peacock M, Nicholson M . Quantitative analysis of calcium-containing urinary calculi. Invest Urol. 1969; 6(6):549-61. View

14.

ZETTNER A, Seligson D . APPLICATION OF ATOMIC ABSORPTION SPECTROPHOTOMETRY IN THE DETERMINATION OF CALCIUM IN SERUM. Clin Chem. 1964; 10:869-90. View

15.

TSAY Y . Application of infrared spectroscopy to analysis of urinary calculi. J Urol. 1961; 86:838-54. DOI: 10.1016/S0022-5347(17)65267-4. View

16.

Maurer C . [Quantitative analysis of urinary concrements]. Urologe. 1969; 8(4):189-93. View

17.

LONSDALE K, Sutor D, Wooley S . Composition of urinary calculi by x-ray diffraction. Collected data from various localities. I. Norwich (England) and District, 1773-1961. Br J Urol. 1968; 40(1):33-6. DOI: 10.1111/j.1464-410x.1968.tb11810.x. View

18.

Kirby J, PELPHREY C, RAINEY Jr J . The analysis of urinary calculi. Am J Clin Pathol. 1957; 27(3):360-2. DOI: 10.1093/ajcp/27.3_ts.360. View

19.

MATHIES J, Lund P . X-ray spectroscopy in biology and medicine. 8. Micro and ultramicro procedures for the quantitative determination of calcium, phosphorus, and sulfur in urinary calculi. Clin Chem. 1967; 13(11):962-9. View