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The Effects of Diversion of Intestinal Contents on the Progress of Crohn's Disease of the Large Bowel

Overview
Journal Gut
Specialty Gastroenterology
Date 1971 Jan 1
PMID 5543369
Citations 28
Authors
J H Burman
H Thompson
W T COOKE
J A Williams
Affiliations
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Abstract

This study shows that faecal diversion by ileostomy or colostomy results in an improvement in the patient's general health which is substantiated by the haematological and biochemical findings. However, in the bowel distal to the diversion there is always histological evidence of mucosal and transmural disease and complications such as fistulae may still occur. In only two patients (7%) was restoration of bowel continuity successful.

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References
1.
OBERHELMAN Jr H, Kohatsu S, Taylor K, KIVEL R . Diverting ileostomy in the surgical management of Crohn's disease of the colon. Am J Surg. 1968; 115(2):231-40. DOI: 10.1016/0002-9610(68)90034-2. View
2.
TRUELOVE S, Ellis H, WEBSTER C . PLACE OF A DOUBLE-BARRELLED ILEOSTOMY IN ULCERATIVE COLITIS AND CROHN'S DISEASE OF THE COLON: A PRELIMINARY REPORT. Br Med J. 1965; 1(5428):150-3. PMC: 2165141. DOI: 10.1136/bmj.1.5428.150. View