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The Effect of Growth Hormone on Fibrinogen Synthesis

Overview
Journal Biochem J
Specialty Biochemistry
Date 1970 Sep 1
PMID 5488913
Citations 6
Authors
K N Jeejeebhoy
A BRUCE-ROBERTSON
U Sodtke
M Foley
Affiliations
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Abstract

A method described by McFarlane (1963a) for the measurement of the absolute rate of synthesis of liver-made plasma proteins was used to show that, within a few hours of giving bovine growth hormone to rats, fibrinogen synthesis increased significantly without a change in albumin synthesis.

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References
1.
McFARLANE A . MEASUREMENT OF SYNTHESIS RATES OF LIVER-PRODUCED PLASMA PROTEINS. Biochem J. 1963; 89:277-90. PMC: 1202359. DOI: 10.1042/bj0890277. View
2.
REEVE E, PEARSON J, MARTZ D . Plasma protein synthesis in the liver: method for measurement of albumin formation in vivo. Science. 1963; 139(3558):914-6. DOI: 10.1126/science.139.3558.914. View
3.
JOHN D, Miller L . Regulation of net biosynthesis of serum albumin and acute phase plasma proteins. Induction of enhanced net synthesis of fibrinogen, alpha1-acid glycoprotein, alpha2 (acute phase)-globulin, and haptoglobin by amino acids and hormones during perfusion.... J Biol Chem. 1969; 244(22):6134-42. View
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Jeejeebhoy K, Samuel A, Singh B, Nadkarni G, Desai H, BORKAR A . Metabolism of albumin and fibrinogen in patients with tropical sprue. Gastroenterology. 1969; 56(2):252-67. View
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Parlow A, WILHELMI A, REICHERT Jr L . Further studies on the fractionation of human pituitary glands. Endocrinology. 1965; 77(6):1126-34. DOI: 10.1210/endo-77-6-1126. View