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Oral Disopyramide in Prophylaxis of Arrhythmias Following Myocardial Infarction

Overview
Journal Lancet
Publisher Elsevier
Specialty General Medicine
Date 1976 Jan 10
PMID 54578
Citations 22
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Abstract

Oral disopyramide given prophylactically following myocardial infarction has been compared with placebo in a double-blind trial using continuous-tape monoriting of the electocardiogram. It caused a significant reduction in the incidence of ventricular arrhythmias and of the various degrees of heart-block. There was a significant reduction of reinfarction during hospital stay in patients who had received disopyramide. Disopyramide appears to be a safe and effective oral therapy in the prevention of potentially serious arrhythmias following myocardial infarction.

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