Active and Passive Immunization in the Adult Rabbit Ileal Loop Model As an Assay for Production of Antitoxin Immunity by Cholera Vaccines

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 1969 Oct 1

PMID 5344118

Citations 3

Authors

W H Mosley

A Ahmed

Affiliations

Soon will be listed here.

Abstract

Three field trial cholera vaccines did not induce antitoxic immunity. A choleragenic toxin induced high-serum neutralizing antibody, but protection to loop challenge with toxin was minimal.

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References

Burrows W, MUSTEIKIS G . Cholera infection and toxin in the rabbit ileal loop. J Infect Dis. 1966; 116(2):183-90. DOI: 10.1093/infdis/116.2.183. View

KASAI G, Burrows W . The titration of cholera toxin and antitoxin in the rabbit ileal loop. J Infect Dis. 1966; 116(5):606-14. DOI: 10.1093/infdis/116.5.606. View

Finkelstein R, Atthasampunna P . Immunity against experimental cholera. Proc Soc Exp Biol Med. 1967; 125(2):465-9. DOI: 10.3181/00379727-125-32121. View

BENENSON A, Saad A, Mosley W . Serological studies in cholera. 2. The vibriocidal antibody response of cholera patients determined by a microtechnique. Bull World Health Organ. 1968; 38(2):277-85. PMC: 2554323. View

BENENSON A, Mosley W, FAHIMUDDIN M, OSEASOHN R . Cholera vaccine field trials in east Pakistan. 2. Effectiveness in the field. Bull World Health Organ. 1968; 38(3):359-72. PMC: 2554494. View