Reduced Adhesiveness Between Skin Fibroblasts from Patients with Duchenne Muscular Dystrophy

Overview

Journal J Neurol Sci

Publisher Elsevier

Specialty Neurology

Date 1979 Nov 1

PMID 521840

Citations 9

Authors

G E Jones

J A Witkowski

Affiliations

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Abstract

The intercellular adhesiveness of skin fibroblasts from patients with Duchenne muscular dystrophy and normal controls has been measured by determining the collision efficencies of cells using the couette viscometer. The collision efficencies for dystrophic cells were significantly lower that those for normal cells (0.01 greater than P greater than 0.005), indicating that dystrophic cells are less adhesive than normal cells.

Citing Articles

Protein degradation in skin fibroblasts from patients with Duchenne muscular dystrophy.

Statham H, Witkowski J, Dubowitz V Biochem J. 1980; 192(1):257-62.

PMID: 7305898 PMC: 1162329. DOI: 10.1042/bj1920257.

A cell surface abnormality in Duchenne muscular dystrophy: intercellular adhesiveness of skin fibroblasts from patients and carriers.

Jones G, Witkowski J Hum Genet. 1983; 63(3):232-7.

PMID: 6852819 DOI: 10.1007/BF00284655.

Abnormal collagen metabolism in cultured skin fibroblasts from patients with Duchenne muscular dystrophy.

Rodemann H, Bayreuther K Proc Natl Acad Sci U S A. 1984; 81(16):5130-4.

PMID: 6591184 PMC: 391651. DOI: 10.1073/pnas.81.16.5130.

Monensin-induced inhibition of cell spreading in normal and dystrophic human fibroblasts.

Pizzey J, Witkowski J, Jones G Proc Natl Acad Sci U S A. 1984; 81(15):4960-4.

PMID: 6589639 PMC: 391612. DOI: 10.1073/pnas.81.15.4960.

Increased rate of cell-substratum detachment of fibroblasts from patients with Duchenne muscular dystrophy.

Kent C Proc Natl Acad Sci U S A. 1983; 80(10):3086-90.

PMID: 6574472 PMC: 393979. DOI: 10.1073/pnas.80.10.3086.