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Clinical Use of Glucagon and Insulin in Therapy of Fulminant Hepatic Failure

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Specialty Gastroenterology
Date 1979 Oct 1
PMID 520769
Citations 7
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Abstract

We have reported 5 cases of fulminant hepatic failure who were treated with a combination of glucagon and insulin. Marked improvement of hepatic coma was characteristically noted in all cases.

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References
1.
Junge U, Creutzfeldt W . Hepatotrophic effects of pancreatic and gastrointestinal hormones in the rat in vivo and in vitro. Ciba Found Symp. 1977; (55):269-83. DOI: 10.1002/9780470720363.ch14. View

2.
Farivar M, Wands J, Isselbacher K, BUCHER N . Effect of insulin and glucagon on fulminant murine hepatitis. N Engl J Med. 1976; 295(27):1517-9. DOI: 10.1056/NEJM197612302952706. View

3.
Chang T . Haemoperfusions over microencapsulated adsorbent in a patient with hepatic coma. Lancet. 1972; 2(7791):1371-2. DOI: 10.1016/s0140-6736(72)92821-8. View

4.
Bucher M, SWAFFIELD M . Regulation of hepatic regeneration in rats by synergistic action of insulin and glucagon. Proc Natl Acad Sci U S A. 1975; 72(3):1157-60. PMC: 432485. DOI: 10.1073/pnas.72.3.1157. View

5.
Soeters P, Fischer J . Insulin, glucagon, aminoacid imbalance, and hepatic encephalopathy. Lancet. 1976; 2(7991):880-2. DOI: 10.1016/s0140-6736(76)90541-9. View