Is Drosophila DAT on the Y Chromosome?

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 1971 Dec 1

PMID 5002284

Citations 20

Authors

M Blumenfled

H S FORREST

Affiliations

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Abstract

DNA isolated from Drosophila melanogaster embryos contains measurable amounts of dAT, the copolymer of deoxyadenylate and deoxythymidylate. In wild-type (XX,XY) embryos, dAT constitutes 4% of the total DNA. In embryos containing extra Y chromosomes, or even extra portions of Y chromosomes, dAT constitutes as much as 7% of the total. The enrichment for dAT is dependent upon the number of extra short arms of the Y chromosome (Y(S)) or long arms (Y(L)) of the Y chromosome per individual. This enrichment of dAT dependent on the Y chromosome may be interpreted in several ways. The most straightforward interpretation is that dAT is present in high concentrations on the Y chromosome.

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