Insulin Levels in Primates by Immunoassay
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Only trace amounts of insulin were detected by an immunoassay system with guinea pig antibody to pork insulin in the New World primates Cebus and Saimiri. The system found insulin levels in the Old World primates rhesus and chimpanzee which were quite like those of human beings. The findings suggest important structural differences in the insulins of the two primate divisions.
Development of metabolic function biomarkers in the common marmoset, Callithrix jacchus.
Ziegler T, Colman R, Tardif S, Sosa M, Wegner F, Wittwer D Am J Primatol. 2013; 75(5):500-8.
PMID: 23447060 PMC: 3771328. DOI: 10.1002/ajp.22126.
Endocrine function in naturally long-living small mammals.
Buffenstein R, Pinto M Mol Cell Endocrinol. 2008; 299(1):101-11.
PMID: 18674586 PMC: 4399555. DOI: 10.1016/j.mce.2008.04.021.
Guinea pig preproinsulin gene: an evolutionary compromise?.
Chan S, Episkopou V, Zeitlin S, Karathanasis S, MacKrell A, Steiner D Proc Natl Acad Sci U S A. 1984; 81(16):5046-50.
PMID: 6591179 PMC: 391634. DOI: 10.1073/pnas.81.16.5046.
Sequence of a New World primate insulin having low biological potency and immunoreactivity.
Seino S, Steiner D, Bell G Proc Natl Acad Sci U S A. 1987; 84(21):7423-7.
PMID: 3118367 PMC: 299308. DOI: 10.1073/pnas.84.21.7423.
Isolation and amino acid sequences of squirrel monkey (Saimiri sciurea) insulin and glucagon.
Yu J, Eng J, Yalow R Proc Natl Acad Sci U S A. 1990; 87(24):9766-8.
PMID: 2263627 PMC: 55254. DOI: 10.1073/pnas.87.24.9766.