Alpha 2.0
Login Register
» Articles » PMID: 4937034

Intramuscular Lignocaine 2 and 10

Overview
Journal Br Med J
Specialty General Medicine
Date 1971 Sep 4
PMID 4937034
Citations 3
Authors
P Jebson
Affiliations
Soon will be listed here.
Abstract

Studies in 10 male volunteers has shown that intramuscular injection of 10% lignocaine produces similar blood lignocaine levels to those obtained with larger volumes of a less concentrated preparation. Since no local or general complications occurred it is suggested that the 10% solution is suitable for clinical use.

Citing Articles

Plasma mexiletine concentrations following combined oral and intramuscular administration.

Bradbrook I, Feldschreiber P, Morrison P, Rogers H, Spector R Eur J Clin Pharmacol. 1981; 19(4):301-4.

PMID: 7286033 DOI: 10.1007/BF00562808.

Neuromuscular blockade in infants following intramuscular succinylcholine in two or five per cent concentration.

Sutherland G, Bevan J, Bevan D Can Anaesth Soc J. 1983; 30(4):342-6.

PMID: 6871775 DOI: 10.1007/BF03007855.

Blood levels of lignocaine after intramuscular administration to patients with proven or suspected acute myocardial infarction.

Ryden L, Wasir H, Conradsson T, Olsson B Br Heart J. 1972; 34(10):1012-7.

PMID: 5086967 PMC: 458539. DOI: 10.1136/hrt.34.10.1012.

References
1.
Keenaghan J . The determination of lidocaine and prilocaine in whole blood by gas chromatography. Anesthesiology. 1968; 29(1):110-2. DOI: 10.1097/00000542-196801000-00029. View
2.
Scott D, Jebson P, Vellani C, Julian D . Plasma-levels of lignocaine after intramuscular injection. Lancet. 1968; 2(7580):1209-10. DOI: 10.1016/s0140-6736(68)91692-9. View
3.
BRAID D, Scott D . THE SYSTEMIC ABSORPTION OF LOCAL ANALGESIC DRUGS. Br J Anaesth. 1965; 37:394-404. DOI: 10.1093/bja/37.6.394. View