Physiological Basis of Transient Repression of Catabolic Enzymes in Escherichia Coli

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 1970 May 1

PMID 4911541

Citations 20

Authors

B Tyler

B MAGASANIK

Affiliations

Soon will be listed here.

Abstract

Transient repression of catabolic enzymes occurs in cells that encounter a new carbon compound in their growth medium, but only when the cells contain the enzyme catalyzing the transfer of phosphate from phosphoenolpyruvate to a small heat-stable protein (HPr), as well as a permease capable of transporting the new compound across the cell membrane. The newly added compound need not be metabolized. The degree and duration of the transient repression have no obvious relation to the intracellular level of the exogenously added compound. It is suggested that the actual passage of the compound through the cell membrane is responsible for the repression.

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