Endonuclease II of E. Coli. I. Isolation and Purification

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 1969 Mar 1

PMID 4895219

Citations 13

Authors

E C Friedberg

D A GOLDTHWAIT

Affiliations

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Abstract

The isolation and purification of a new endonuclease of E. coli is described. This enzyme degrades alkylated DNA as assayed by a technique that requires double-strand scission. The enzyme also makes a limited number of single-strand breaks in native nonalkylated DNA.

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