» Articles » PMID: 4873809

Leigh's Encephalomyelopathy: an Inborn Error of Gluconeogenesis

Overview
Journal Arch Dis Child
Specialty Pediatrics
Date 1968 Aug 1
PMID 4873809
Citations 38
Authors
Affiliations
Soon will be listed here.
Citing Articles

Development of iPSC-based clinical trial selection platform for patients with ultrarare diseases.

Sequiera G, Srivastava A, Sareen N, Yan W, Alagarsamy K, Verma E Sci Adv. 2022; 8(14):eabl4370.

PMID: 35394834 PMC: 8993122. DOI: 10.1126/sciadv.abl4370.


On the dynamic and even reversible nature of Leigh syndrome: Lessons from human imaging and mouse models.

Walker M, Miranda M, Allred A, Mootha V Curr Opin Neurobiol. 2021; 72:80-90.

PMID: 34656053 PMC: 8901530. DOI: 10.1016/j.conb.2021.09.006.


Leigh Syndrome: A Tale of Two Genomes.

Bakare A, Lesnefsky E, Iyer S Front Physiol. 2021; 12:693734.

PMID: 34456746 PMC: 8385445. DOI: 10.3389/fphys.2021.693734.


Neuroprotective role of lipoic acid against acute toxicity of N-acetylaspartic acid.

Pederzolli C, Rosa A, de Oliveira A, Coelho J, da Luz Becker D, Dalazen G Mol Cell Biochem. 2010; 344(1-2):231-9.

PMID: 20686917 DOI: 10.1007/s11010-010-0547-x.


Mitochondrial DNA 11777C>A mutation associated Leigh syndrome: case report with a review of the previously described pedigrees.

Hadzsiev K, Maasz A, Kisfali P, Kalman E, Gomori E, Pal E Neuromolecular Med. 2010; 12(3):277-84.

PMID: 20502985 DOI: 10.1007/s12017-010-8115-9.


References
1.
WORSLEY H, BROOKFIELD R, ELWOOD J, NOBLE R, Taylor W . Lactic acidosis with necrotizing encephalopathy in two sibs. Arch Dis Child. 1965; 40(213):492-501. PMC: 2019452. DOI: 10.1136/adc.40.213.492. View

2.
EBELS E, BLOKZIJL E, TROELSTRA J . A Wernicke-like encephalomyelopathy in children (Leigh), an inborn error of metabolism? Report of 5 cases with emphasis on its familial incidence. Helv Paediatr Acta. 1965; 20(3):310-24. View

3.
Lakke J, EBELS E, ten Thye O . Infantile necrotizing encephalomyelopathy (Leigh). Arch Neurol. 1967; 16(3):227-31. DOI: 10.1001/archneur.1967.00470210003001. View

4.
Rolleston F, Newsholme E . Effects of fatty acids, ketone bodies, lactate and pyruvate on glucose utilization by guinea-pig cerebral cortex slices. Biochem J. 1967; 104(2):519-23. PMC: 1270614. DOI: 10.1042/bj1040519. View

5.
Clayton B, Dobbs R, PATRICK A . Leigh's subacute necrotizing encephalopathy: clinical and biochemical study, with special reference to therapy with lipoate. Arch Dis Child. 1967; 42(225):467-78. PMC: 2019798. DOI: 10.1136/adc.42.225.467. View