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Selective Inhibition of Newcastle Disease Virus-induced Glycoprotein Synthesis by D-glucosamine Hydrochloride

Overview
Journal J Virol
Publisher American Society for Microbiology
Date 1974 Apr 1
PMID 4821488
Citations 5
Authors
A C Samson
C F Fox
Affiliations
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Abstract

d-Glucosamine selectively affected the synthesis of virus-induced glycoproteins in Newcastle disease virus-infected chick fibroblasts, but had no effect upon post-translational cleavage of the glycoprotein precursor for one of the two major glycoproteins of the mature virion. In response to glucosamine, at least one of the two virus-induced glycoproteins is formed in reduced quantity and the second is either not formed or has an electrophoretic mobility identical to that of another virus-induced protein.

Citing Articles

Synthesis, stability, and cleavage of Newcastle disease virus glycoproteins in the absence of glycosylation.

Morrison T, Simpson D J Virol. 1980; 36(1):171-80.

PMID: 7441820 PMC: 353628. DOI: 10.1128/JVI.36.1.171-180.1980.

Relationships among the polypeptides of Newcastle disease virus.

Hightower L, Morrison T, Bratt M J Virol. 1975; 16(6):1599-607.

PMID: 1202248 PMC: 355769. DOI: 10.1128/JVI.16.6.1599-1607.1975.

Polypeptide synthesis in simian virus 5-infected cells.

Peluso R, Lamb R, Choppin P J Virol. 1977; 23(1):177-87.

PMID: 196101 PMC: 515813. DOI: 10.1128/JVI.23.1.177-187.1977.

In vivo antiviral activity of D-glucosamine.

Floch F, WERNER G Arch Virol. 1976; 52(1-2):169-73.

PMID: 187148 DOI: 10.1007/BF01317877.

Biological and physical modifications of a murine oncornavirus by 2-deoxy-D-glucose.

Prochownik E, Panem S, Kirsten W J Virol. 1975; 15(6):1323-31.

PMID: 49438 PMC: 354599. DOI: 10.1128/JVI.15.6.1323-1331.1975.

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