Action of Staphylococcal Alpha-toxin on Membranes: Some Recent Advances

Overview

Journal Mol Cell Biochem

Publisher Springer

Specialty Biochemistry

Date 1979 Feb 9

PMID 481427

Citations 14

Authors

S HARSHMAN

Affiliations

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Abstract

Recent developments in the area of Staphylococcal alpha-toxin studies are presented which modify the concepts previously held with respect to both biological and physical properties of alpha-toxin. New data concerning the nature of the binding site for alpha-toxin on rabbit erythrocyte membranes and a model to explain the various observed complexes of alpha-toxin and membrane receptor are discussed. Finally, evidence suggesting that Staphylococcal alpha-toxin is a potent demyelinating agent is presented.

Citing Articles

Induction of muscle-relaxing factor by staphylococcal alpha-toxin.

HARSHMAN S, Sugg N Infect Immun. 1994; 62(2):421-5.

PMID: 8300202 PMC: 186124. DOI: 10.1128/iai.62.2.421-425.1994.

Transport and processing of staphylococcal alpha-toxin.

Tweten R, Christianson K, Iandolo J J Bacteriol. 1983; 156(2):524-8.

PMID: 6630145 PMC: 217863. DOI: 10.1128/jb.156.2.524-528.1983.

In vivo and in vitro studies of bacterial endotoxin-membrane interactions and the effects of membrane-active agents.

Garnett M, Godin D, Tuchek J Br J Pharmacol. 1984; 83(1):15-21.

PMID: 6386087 PMC: 1987181. DOI: 10.1111/j.1476-5381.1984.tb10114.x.

On the mechanism of membrane damage by Staphylococcus aureus alpha-toxin.

Fussle R, Bhakdi S, Sziegoleit A, Tranum-Jensen J, Kranz T, WELLENSIEK H J Cell Biol. 1981; 91(1):83-94.

PMID: 6271794 PMC: 2111936. DOI: 10.1083/jcb.91.1.83.

Susceptibility to staphylococcal alpha-toxin of Friend virus-infected murine erythroblasts during differentiation.

HARSHMAN S, Bondurant M Infect Immun. 1985; 48(1):114-8.

PMID: 3980078 PMC: 261922. DOI: 10.1128/iai.48.1.114-118.1985.

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