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Metabolism of Biphenyl. 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate: the Meta-cleavage Product from 2,3-dihydroxybiphenyl by Pseudomonas Putida

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Journal Biochem J
Specialty Biochemistry
Date 1973 Aug 1
PMID 4762751
Citations 27
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Abstract

1. 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid was isolated and identified from washed suspensions of Pseudomonas putida incubated in the presence of 2,3-dihydroxybiphenyl. 2. Benzoic acid was isolated from reaction mixtures of crude cell-free extracts incubated with 2,3-dihydroxybiphenyl. 3. The presence in the same reaction mixtures of either 4-hydroxy-2-oxovalerate or 2-hydroxypenta-2,4-dienoate was suggested by mass spectrometry. 4. The degradative pathway of biphenyl is discussed.

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