Some Factors Indicative of Hypertriglyceridemia in Patients Investigated for Diabetes Mellitus

Overview

Journal Can Med Assoc J

Specialty General Medicine

Date 1973 Sep 1

PMID 4742474

Citations 2

Authors

N W Rodger

E L Du

Affiliations

Soon will be listed here.

Abstract

A study was done of 160 patients with abnormal blood glucose levels, 91 (57%) of whom fulfilled standard criteria for the diagnosis of diabetes mellitus. The overall prevalence (36%) and the age-related characteristics of fasting hypertriglyceridemia were similar to distributions reported in groups of patients with coronary artery disease. Fasting hypercholesterolemia occurred in four patients (2.5%), in three of whom there was evidence of associated hyperchylomicronemia on lipoprotein electrophoresis. For effective application of the OGTT response to the detection of hypertriglyceridemic patients, somewhat lower blood glucose levels than those generally accepted for the diagnosis of diabetes mellitus are necessary. Fasting hyperglycemia and the retention of body weight gained after age 25 were features of hypertriglyceridemic patients. Insufficient basal insulin action could explain the development of fasting hypertriglyceridemia in patients in whom the diagnosis of diabetes mellitus is being considered.

Citing Articles

Plasma triglycerides in human diabetes.

NIKKILA E Proc R Soc Med. 1974; 67(7):662-5.

PMID: 4212245 PMC: 1651737.

Lipid abnormalities in untreated maturity-onset diabetics and the effect of treatment.

Simpson R, Mann J, Hockaday T, HOCKADAY J, Turner R, Jelfs R Diabetologia. 1979; 16(2):101-6.

PMID: 759252 DOI: 10.1007/BF01225458.

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