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Specific Monovalent Cation Effects on Modification of Reovirus Infectivity by Chymotrypsin Digestion in Vitro

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Journal J Virol
Date 1973 Jun 1
PMID 4736532
Citations 6
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Abstract

Specific monovalent cations control the modification of reovirus infectivity by chymotrypsin. Digestion in K(+), Rb(+), or Cs(+) reduces infectivity several logs, whereas in Na(+) or Li(+) digestion markedly enhances infectivity.

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References
1.
Borsa J, Copps T, Sargent M, Long D, Chapman J . New intermediate subviral particles in the in vitro uncoating of reovirus virions by chymotrypsin. J Virol. 1973; 11(4):552-64. PMC: 355137. DOI: 10.1128/JVI.11.4.552-564.1973. View

2.
Spendlove R, SCHAFFER F . ENZYMATIC ENHANCEMENT OF INFECTIVITY OF REOVIRUS. J Bacteriol. 1965; 89:597-602. PMC: 277508. DOI: 10.1128/jb.89.3.597-602.1965. View

3.
Wallis C, Melnick J, Rapp F . Effects of pancreatin on the growth of reovirus. J Bacteriol. 1966; 92(1):155-60. PMC: 276210. DOI: 10.1128/jb.92.1.155-160.1966. View

4.
Spendlove R, McClain M, LENNETTE E . Enhancement of reovirus infectivity by extracellular removal or alteration of the virus capsid by proteolytic enzymes. J Gen Virol. 1970; 8(2):83-94. DOI: 10.1099/0022-1317-8-2-83. View

5.
Joklik W . Studies on the effect of chymotrypsin on reovirions. Virology. 1972; 49(3):700-15. DOI: 10.1016/0042-6822(72)90527-2. View