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Norephedrines As Metabolites of ( 14 C)amphetamine in Urine in Man

Overview
Journal Biochem J
Specialty Biochemistry
Date 1972 Aug 1
PMID 4646777
Citations 10
Authors
J Caldwell
L G Dring
R T Williams
Affiliations
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Abstract

(+/-)-[(14)C]Amphetamine sulphate (20mg) was administered orally to each of two human male subjects, and 80-85% of the (14)C was excreted in the urine in 2 days. The metabolites in the first day's urine were examined quantitatively. Apart from the metabolites previously described (Dring et al., 1970), norephedrine (2.2 and 2.6% of dose in the two subjects respectively) and 4-hydroxynorephedrine (0.3 and 0.4% of dose in the two subjects respectively) were also found.

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References
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