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A Strategy of DNA Sequencing Employing Computer Programs

Overview
Journal Nucleic Acids Res
Publisher Oxford University Press
Specialty Biochemistry
Date 1979 Jun 11
PMID 461197
Citations 129
Authors
R Staden
Affiliations
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Abstract

With modern fast sequencing techniques and suitable computer programs it is now possible to sequence whole genomes without the need of restriction maps. This paper describes computer programs that can be used to order both sequence gel readings and clones. A method of coding for uncertainties in gel readings is described. These programs are available on request.

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References
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