Interspecies Conversion of Clostridium Botulinum Type C to Clostridium Novyi Type A by Bacteriophage

Overview

Journal Science

Specialty Science

Date 1974 Nov 1

PMID 4606682

Citations 24

Authors

M W Eklund

F T Poysky

J A Meyers

G A Pelroy

Affiliations

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Abstract

When Clostridium botulinum type C is cured of its prophage it simultaneously ceases to produce toxin. This nontoxigenic culture can then be converted to another toxigenic bacterial species, Clostridium novyi type A or to toxigenic Clostridium botulinum types C or D, by specific bacteriophages. The toxigenicity and type of toxin produced by these cultures depends upon the continued presence of these bacteriophages.

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