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Immunocytoadherence During Experimental Histoplasmosis

Overview
Journal Infect Immun
Publisher American Society for Microbiology
Specialty Allergy & Immunology
Date 1974 Jul 1
PMID 4601766
Citations 1
Authors
G D Roberts
H W LARSH
Affiliations
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Abstract

Immunocytoadherence was investigated as a method of detecting active histoplasmosis in two groups of infected New Zealand white rabbits. Yeast-phase Histoplasma capsulatum was given intravenously to one group and intratracheally to the other. There was a striking correlation between the clinical condition of the animals and the number of rosettes seen. This number increased as the infection progressed and decreased as it regressed. The immunocytoadherence technique might be of value in detecting active histoplasmosis, and investigation in humans is warranted.

Citing Articles

Rosette-forming cells during immune response to Toxoplasma gondii in mice.

Masihi K, Werner H Infect Immun. 1976; 13(6):1678-83.

PMID: 971946 PMC: 420819. DOI: 10.1128/iai.13.6.1678-1683.1976.

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