» Articles » PMID: 4589122

Microbial Reduction of Ketopantoyl Lactone to Pantoyl Lactone

Overview
Journal Appl Microbiol
Specialty Microbiology
Date 1974 Jan 1
PMID 4589122
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

The results of a microbial survey study have shown that the ability to reduce added ketopantoic acid (or ketopantoyl lactone) and accumulate pantoic acid (or pantoyl lactone) in the growth medium is widespread among diverse fungi. The reductions generally proceeded with less than full stereoselectivity. However, specific strains of the ascomycete Byssochlamys fulva were found to form D[-]-pantoic acid in unusually high yields and optical purity.

Citing Articles

One-Step Microbial Conversion of a Racemic Mixture of Pantoyl Lactone to Optically Active d-(-)-Pantoyl Lactone.

Shimizu S, Hattori S, Hata H, Yamada H Appl Environ Microbiol. 1987; 53(3):519-22.

PMID: 16347301 PMC: 203699. DOI: 10.1128/aem.53.3.519-522.1987.

References
1.
Van de Putte P, Westenbroek C, ROERSCH A . THE RELATIONSHIP BETWEEN GENE-CONTROLLED RADIATION RESISTANCE AND FILAMENT FORMATION IN ESCHERICHIA COLI. Biochim Biophys Acta. 1963; 76:247-56. DOI: 10.1016/0006-3002(63)90037-4. View

2.
Kirby E, RUFF W, GOLDTHWAIT D . Cell division and prophage induction in Escherichia coli: effects of pantoyl lactone and various furan derivatives. J Bacteriol. 1972; 111(2):447-53. PMC: 251303. DOI: 10.1128/jb.111.2.447-453.1972. View

3.
LANSFORD E, SHIVE W . The microbiological activity of alpha-keto-beta beta-dimethyl-alpha-butyrolactone. Arch Biochem Biophys. 1952; 38:353-5. DOI: 10.1016/0003-9861(52)90040-4. View

4.
Grula E, GRULA M . Cell division in a species of Erwinia III. Reversal of inhibition of cell division caused by D-amino acids, penicillin, and ultraviolet light. J Bacteriol. 1962; 83:981-8. PMC: 279397. DOI: 10.1128/jb.83.5.981-988.1962. View

5.
MacLeod R, Prosser H, FIKENTSCHER L, LANYI J, MOSHER H . ASYMMETRIC REDUCTIONS. 12. STEREOSELECTIVE KETONE REDUCTIONS BY FERMENTING YEAST. Biochemistry. 1964; 3:838-46. DOI: 10.1021/bi00894a020. View