Pyelonephritis. XIV. Effect of Immunization on Experimental Escherichia Coli Pyelonephritis

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1972 Sep 1

PMID 4564890

Citations 2

Authors

J Z Montgomerie

G M KALMANSON

E G Hubert

L B Guze

Affiliations

Soon will be listed here.

Abstract

Mice immunized subcutaneously with heat-killed Escherichia coli were protected from pyelonephritis produced by the intravenous route, but there was little or no protection from ascending infection. No significant protection from ascending or hematogenous pyelonephritis was demonstrated when immunization was accomplished by injecting heat-killed E. coli into the bladder. Heat-killed E. coli injected either subcutaneously or into the bladder protected mice from early endotoxic death after intravenous or bladder challenge.

Citing Articles

P-fimbriae vaccines. II. Cross reactive protection against pyelonephritis.

Roberts J, Kaack M, Baskin G, Korhonen T, Svenson S, Winberg J Pediatr Nephrol. 1989; 3(4):391-6.

PMID: 2577147 DOI: 10.1007/BF00850213.

Antigen presentation as a factor in the protective immune response to renal infection.

Miller T, Burnham S Clin Exp Immunol. 1975; 22(2):265-78.

PMID: 765022 PMC: 1538299.

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