Lack of Supportive Evidence for an Autosomal Recessive Inheritance in Chronic Hepatitis B Infections

Overview

Journal Dig Dis Sci

Specialty Gastroenterology

Date 1979 Apr 1

PMID 456216

Authors

M J Tong

J M Weiner

Affiliations

Soon will be listed here.

Abstract

Two families with persistent hepatitis B infections are described. The patterns of HBsAG positivity in the parents and offspring are not compatible with the theory that susceptibility to chronic hepatitis B infection is inherited as an autosomal recessive trait.

References

Nordenfelt E, Kjellen L . Dane particles, DNA polymerase, and e-antigen in two different categories of hepatitis B antigen carriers. Intervirology. 1975; 5(3-4):225-32. DOI: 10.1159/000149918. View

Okada K, Kamiyama I, Inomata M, Imai M, Miyakawa Y . e antigen and anti-e in the serum of asymptomatic carrier mothers as indicators of positive and negative transmission of hepatitis B virus to their infants. N Engl J Med. 1976; 294(14):746-9. DOI: 10.1056/NEJM197604012941402. View

SCHWEITZER I . Infection of neonates and infants with the hepatitis B virus. Prog Med Virol. 1975; 20:27-48. View

VYAS G, Shulman N . Hemagglutination assay for antigen and antibody associated with viral hepatitis. Science. 1970; 170(3955):332-3. DOI: 10.1126/science.170.3955.332. View

Blumberg B, Friedlaender J, Woodside A, Sutnick A, London W . Hepatitis and Australia antigen: autosomal recessive inheritance of susceptibility to infection in humans. Proc Natl Acad Sci U S A. 1969; 62(4):1108-15. PMC: 223621. DOI: 10.1073/pnas.62.4.1108. View

Tong M, Stevenson D, Gordon I . Correlation of e antigen, DNA polymerase activity, and Dane particles in chronic benign and chronic active type B hepatitis infections. J Infect Dis. 1977; 135(6):980-4. DOI: 10.1093/infdis/135.6.980. View

Stevens C, Beasley R . Lack of an autosomal recessive genetic influence in vertical transmission of hepatitis B antigen. Nature. 1976; 260(5553):715-6. DOI: 10.1038/260715a0. View

Stevens C, Beasley R, Tsui J, Lee W . Vertical transmission of hepatitis B antigen in Taiwan. N Engl J Med. 1975; 292(15):771-4. DOI: 10.1056/NEJM197504102921503. View

VYAS G . Evidence against recessive inheritance of susceptibility to the chronic carrier state for hepatitis B antigen. Nature. 1974; 248(5444):159-60. DOI: 10.1038/248159a0. View

10.

SZMUNESS W, Harley E, Prince A . Intrafamilial spread of asymptomatic hepatitis B. Am J Med Sci. 1975; 270(2):293-304. DOI: 10.1097/00000441-197509000-00009. View

11.

SCHWEITZER I, DUNN A, Peters R, SPEARS R . Viral hepatitis b in neonates and infants. Am J Med. 1973; 55(6):762-71. DOI: 10.1016/0002-9343(73)90257-x. View

12.

Okada K, Yamada T, Miyakawa Y, Mayumi M . Hepatitis B surface antigen in the serum of infants after deliver from asymptomatic carrier mothers. J Pediatr. 1975; 87(3):360-3. DOI: 10.1016/s0022-3476(75)80635-4. View

13.

Lam K, Tong M, Rakela J . Release of e antigen from a Dane particle-rich preparation of hepatitis B virus. Infect Immun. 1977; 16(1):403-4. PMC: 421535. DOI: 10.1128/iai.16.1.403-404.1977. View

14.

Skinhoj P, Cohn J, Bradburne A . Transmission of hepatitis type B from healthy HBsAg-positive mothers. Br Med J. 1976; 1(6000):10-11. PMC: 1638220. DOI: 10.1136/bmj.1.6000.10. View