Ly-4, a New Locus Determining a Lymphocyte Cell-surface Alloantigen in Mice

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 1973 Apr 1

PMID 4515607

Citations 28

Authors

G D Snell

M Cherry

I F McKenzie

D W Bailey

Affiliations

Soon will be listed here.

Abstract

A new locus is described that determines an alloantigen on the surface of lymphocytes. It differs from loci previously described in that the corresponding antibody, at least in most antisera, reacts almost exclusively with node lymphocytes, and weakly or not at all with thymuslymphocytes. Positive strains include C57BL/6, C57BL/10, C57L, C57BR/cd, and RF; negative strains include BALB/c, C3H, and SJL. The symbol Ly-4 is assigned, with the C57BL/6 allele being Ly-4(b), and the BALB/c allele Ly-4(a).

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