[Enzymes of Thymidine and Thymidylate Metabolism in Normal and Pathological Blood and Bone Marrow Cells]

Overview

Journal Blut

Specialty Hematology

Date 1972 Nov 1

PMID 4508724

Citations 2

Authors

S Schollenberger

D Taureck

W Wilmanns

Affiliations

Soon will be listed here.

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References

Fausto N, VANLANCKER J . MOLECULAR MECHANISMS OF LIVER REGENERATION. IV. THYMIDYLIC KINASE AND DEOXYRIBONUCLEIC ACID POLYMERASE ACTIVITIES IN NORMAL AND REGENERATING LIVER. J Biol Chem. 1965; 240:1247-55. View

Wilmanns W . [Thymidine kinase in normal and leukemic myeloid cells]. Klin Wochenschr. 1967; 45(10):505-11. DOI: 10.1007/BF01716365. View

Gray E, Weissman S, Richards J, Bell D, Keir H, SMELLIE R . Studies onnthe biosynthesis of deoxyribonucleic acid by extracts of mammalian cells. V. Factors interfering with biosynthesis. Biochim Biophys Acta. 1960; 45:111-20. DOI: 10.1016/0006-3002(60)91431-1. View

Roth J . A hypothesis concerning patterns of deoxynucleotide metabolism in tumors in relation to rate of cell proliferation. J Theor Biol. 1963; 4(1):113-23. DOI: 10.1016/0022-5193(63)90104-8. View

McDougall B, Blakley R . The biosynthesis of thymidylic acid. I. Preliminary studies with extracts of Streptococcus faecalis R. J Biol Chem. 1961; 236:832-7. View

Eker P . PROPERTIES AND ASSAY OF THYMINE DEOXYRIBONUCLEOTIDE PHOSPHATASE OF MAMMALIAN CELLS IN TISSUE CULTURE. J Biol Chem. 1965; 240:419-22. View

GRAV H, SMELLIE R . FRACTIONATION OF THYMIDINE PHOSPHOKINASE, THYMIDINE 5'-MONOPHOSPHATE PHOSPHOKINASE AND THYMIDINE 5'-DIPHOSPHATE PHOSPHOKINASE IN EXTRACTS OF LANDSCHUTZ ASCITES-TUMOUR CELLS. Biochem J. 1965; 94:518-24. PMC: 1206583. DOI: 10.1042/bj0940518. View

BREITMAN T, Perry S, Cooper R . Pyrimidine metabolism in human leukocytes. 3. The utilization of thymine for DNA-thymine synthesis by leukemic leukocytes. Cancer Res. 1966; 26(11):2282-5. View

Wahba A, FRIEDKIN M . The enzymatic synthesis of thymidylate. I. Early steps in the purification of thymidylate synthetase of Escherichia coli. J Biol Chem. 1962; 237:3794-801. View

10.

Manson L, LAMPEN J . The metabolism of desoxyribose nucleosides in Escherichia coli. J Biol Chem. 1951; 193(2):539-47. View

11.

Bianchi P . Thymidine phosphorylation and deoxyribonucleic acid synthesis in human leukaemic cells. Biochim Biophys Acta. 1962; 55:547-9. DOI: 10.1016/0006-3002(62)90989-7. View

12.

IVES D . EVIDENCE FOR THYMIDINE DIPHOSPHATE AS THE PRECURSOR OF THYMIDINE TRIPHOSPHATE IN TUMOR. TRANSFER OF THE TERMINAL PHOSPHATE OF ADENOSINE TRIPHOSPHATE TO THYMIDYLATE. J Biol Chem. 1965; 240:819-24. View

13.

Gallo R, Perry S, BREITMAN T . The enzymatic mechanisms for deoxythymidine synthesis in human leukocytes. I. Substrate inhibition by thymine and activation by phosphate or arsenate. J Biol Chem. 1967; 242(21):5059-68. View

14.

PASTORE E, FRIEDKIN M . The enzymatic synthesis of thymidylate. II. Transfer of tritium from tetrahydrofolate to the methyl group of thymidylate. J Biol Chem. 1962; 237:3802-10. View

15.

BOCK H, Wilms K, Wilmanns W . [Infectious mononucleosis. Leukocyte DNA-synthesis and cell reaction to phytohemagglutinin in cell culture]. Dtsch Med Wochenschr. 1970; 95(14):748-53. DOI: 10.1055/s-0028-1108535. View

16.

Gallo R, Perry S . The enzymatic mechanisms for deoxythymidine synthesis in human leukocytes. IV. Comparisons between normal and leukemic leukocytes. J Clin Invest. 1969; 48(1):105-16. PMC: 322196. DOI: 10.1172/JCI105958. View

17.

NAKAI G, Michael E, Peterson M, CRADDOCK C . Thymidine and thymidylate kinase, and thymidylate phosphatase in human leukemic leukocytes. Clin Chim Acta. 1966; 14(3):422-5. DOI: 10.1016/0009-8981(66)90129-x. View

18.

BUKOVSKY J, Roth J . Studies on thymidylate phosphatase, thymidine kinase and thymidylate kinase activities in some transplantable rat hepatomas. Adv Enzyme Regul. 1964; 2:371-82. DOI: 10.1016/s0065-2571(64)80026-1. View

19.

IVES D, Morse Jr P, POTTER V . Feedback inhibition of thymodine kinase by thymodine triphosphate. J Biol Chem. 1963; 238:1467-74. View

20.

FRIEDKIN M, CRAWFORD E, Donovan E, PASTORE E . The enzymatic synthesis of thymidylate. III. The further purification of thymidylate synthetase and its separation from natural fluorescent inhibitors. J Biol Chem. 1962; 237:3811-4. View