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X-ray Diffraction Studies of Lecithin Bimolecular Leaflets with Incorporated Fluorescent Probes

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Specialty Science
Date 1972 Jun 1
PMID 4504365
Citations 29
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Abstract

X-ray diffraction studies on dispersions and oriented multilayers of dipalmitoyllecithin and different fluorescent probe molecules are reported. Analysis of the diffraction data provides the electron density profile for the different bilayers to 6- to 8-Angstrom resolution. The location of the probe molecules in the bilayer structure and the perturbation of the lecithin bilayer produced by the probes are discussed.

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References
1.
Azzi A, Chance B, Radda G, Lee C . A fluorescence probe of energy-dependent structure changes in fragmented membranes. Proc Natl Acad Sci U S A. 1969; 62(2):612-9. PMC: 277854. DOI: 10.1073/pnas.62.2.612. View

2.
Gitler C, Rubalcava B, Caswell A . Fluorescence changes of ethidium bromide on binding to erythrocyte and mitochondrial membranes. Biochim Biophys Acta. 1969; 193(2):479-81. DOI: 10.1016/0005-2736(69)90208-9. View

3.
Libertini L, Waggoner A, Jost P, Griffith O . Orientation of lipid spin labels in lecithin multilayers. Proc Natl Acad Sci U S A. 1969; 64(1):13-9. PMC: 286119. DOI: 10.1073/pnas.64.1.13. View

4.
Levine Y, Wilkins M . Structure of oriented lipid bilayers. Nat New Biol. 1971; 230(11):69-72. DOI: 10.1038/newbio230069a0. View

5.
Wilkins M, Blaurock A, Engelman D . Bilayer structure in membranes. Nat New Biol. 1971; 230(11):72-6. DOI: 10.1038/newbio230072a0. View