Direct Radioimmunoassay of Human Renin

Overview

Journal J Clin Endocrinol Metab

Publisher Oxford University Press

Specialty Endocrinology

Date 1979 Jun 1

PMID 447794

Citations 10

Authors

F X Galen

T T Guyenne

C Devaux

C Auzan

P Corvol

J Menard

Affiliations

Soon will be listed here.

Abstract

Antibodies were raised in rabbit against pure human renin. The antisera obtained are highly specific for human renin versus hog, dog and rat renin. They do not cross-react with acid proteases such as pepsin and human cathepsin D. A direct radioimunoassay is described for human renin in plasma and kidney extracts. 30 to 50 pg of enzyme (2.5 to 4 x 10(-5) Goldblatt units) are detected.

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