Use of Plasma Catecholamine Values in Diagnosing Pheochromocytoma and Neuroblastoma

Overview

Journal Can Med Assoc J

Specialty General Medicine

Date 1974 Dec 21

PMID 4442016

Citations 1

Authors

F Y Leung

J Griffiths

Affiliations

Soon will be listed here.

Abstract

The diagnosis in two cases of neural crest tumours was confirmed by the measurement of concentration of plasma catecholamines. A histamine provocative test monitored by values of plasma catecholamines provided support for a diagnosis of pheochromocytoma in a patient with normal blood pressure and elevated values of urinary amines. In the second case the presence of a ganglioneuroblastoma secreting abnormal amounts of catecholamines was detected by plasma epinephrine and norepinephrine measurements when values of urinary free catecholamines were normal.

Citing Articles

Adult adrenal neuroblastoma: A case report.

Xu S, Zhang W, Che B, Zhang J, He J, Liu D Mol Clin Oncol. 2021; 15(5):225.

PMID: 34548924 PMC: 8447177. DOI: 10.3892/mco.2021.2378.

References

Thomas J, ROOKE E, KVALE W . The neurologist's experience with pheochromocytoma. A review of 100 cases. JAMA. 1966; 197(10):754-8. View

WEIL-MALHERBE H . The estimation of total (free + conjugated) catecholamines and some catecholamine metabolites in human urine. Methods Biochem Anal. 1968; 16:293-326. DOI: 10.1002/9780470110348.ch6. View

Sheps S, MAHER F . Histamine and glucagon tests in diagnosis of pheochromocytoma. JAMA. 1968; 205(13):895-9. View

Hinterberger H, BARTHOLOMEW R . Catecholamines and their acidic metabolites in urine and in tumour tissue in neuroblastoma, ganglioneuroma and phaeochromocytoma. Clin Chim Acta. 1969; 23(1):169-75. DOI: 10.1016/0009-8981(69)90024-2. View

Engelman K, Portnoy B . A sensitive double-isotope derivative assay for norepinephrine and epinephrine. Normal resting human plasma levels. Circ Res. 1970; 26(1):53-7. DOI: 10.1161/01.res.26.1.53. View