Nature of the Scrapie Agent: Evidence Against a Viroid

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 1974 Nov 1

PMID 4372389

Citations 4

Authors

R L Ward

D D PORTER

J G Stevens

Affiliations

Soon will be listed here.

Abstract

The postulated viroid nature of scrapie agent was tested. Since the agent could not be recovered after a carefully controlled phenol extraction of infected mouse brains, it is suggested that this agent is not a viroid.

Citing Articles

Viroids and prions.

Diener T, McKinley M, Prusiner S Proc Natl Acad Sci U S A. 1982; 79(17):5220-4.

PMID: 6813855 PMC: 346867. DOI: 10.1073/pnas.79.17.5220.

Molecular hybridization studies with scrapie brain nucleic acids. I. Search for specific DNA sequences.

Borras T, Gibbs Jr C Arch Virol. 1986; 88(1-2):67-78.

PMID: 3082311 DOI: 10.1007/BF01310891.

Inactivation of poliovirus in digested sludge.

Ward R, Ashley C Appl Environ Microbiol. 1976; 31(6):921-30.

PMID: 180887 PMC: 169857. DOI: 10.1128/aem.31.6.921-930.1976.

Properties of the scrapie agent-endomembrane complex from hamster brain.

Semancik J, Marsh R, Geelen J, Hanson R J Virol. 1976; 18(2):693-700.

PMID: 131866 PMC: 515597. DOI: 10.1128/JVI.18.2.693-700.1976.

References

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