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Rid Enhances the 6-Hydroxypseudooxynicotine Dehydrogenase Reaction in Nicotine Degradation by Agrobacterium tumefaciens S33.
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RidA Proteins Protect against Metabolic Damage by Reactive Intermediates.
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Reactive Enamines and Imines In Vivo: Lessons from the RidA Paradigm.
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Trends Biochem Sci. 2019; 44(10):849-860.
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Int J Mol Sci. 2018; 19(4).
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Mmf1p Couples Amino Acid Metabolism to Mitochondrial DNA Maintenance in .
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mBio. 2018; 9(1).
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Members of the Rid protein family have broad imine deaminase activity and can accelerate the Pseudomonas aeruginosa D-arginine dehydrogenase (DauA) reaction in vitro.
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PLoS One. 2017; 12(9):e0185544.
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From microbiology to cancer biology: the Rid protein family prevents cellular damage caused by endogenously generated reactive nitrogen species.
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Mol Microbiol. 2015; 96(2):211-9.
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Arabidopsis and maize RidA proteins preempt reactive enamine/imine damage to branched-chain amino acid biosynthesis in plastids.
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Endogenous synthesis of 2-aminoacrylate contributes to cysteine sensitivity in Salmonella enterica.
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Decreased coenzyme A levels in ridA mutant strains of Salmonella enterica result from inactivated serine hydroxymethyltransferase.
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Mol Microbiol. 2013; 89(4):751-9.
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In the absence of RidA, endogenous 2-aminoacrylate inactivates alanine racemases by modifying the pyridoxal 5'-phosphate cofactor.
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J Bacteriol. 2013; 195(16):3603-9.
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RidA proteins prevent metabolic damage inflicted by PLP-dependent dehydratases in all domains of life.
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mBio. 2013; 4(1):e00033-13.
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Anthranilate phosphoribosyl transferase (TrpD) generates phosphoribosylamine for thiamine synthesis from enamines and phosphoribosyl pyrophosphate.
Lambrecht J, Downs D
ACS Chem Biol. 2012; 8(1):242-8.
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Crystal structure of Escherichia coli diaminopropionate ammonia-lyase reveals mechanism of enzyme activation and catalysis.
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J Biol Chem. 2012; 287(24):20369-81.
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Conserved YjgF protein family deaminates reactive enamine/imine intermediates of pyridoxal 5'-phosphate (PLP)-dependent enzyme reactions.
Lambrecht J, Flynn J, Downs D
J Biol Chem. 2011; 287(5):3454-61.
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