Insecticide Inhibition of 5alpha-dihydrotestosterone Binding in the Rat Ventral Prostate

Overview

Journal Science

Specialty Science

Date 1973 Aug 17

PMID 4353358

Citations 3

Authors

A E Wakeling

W J VISEK

Affiliations

Soon will be listed here.

Abstract

The chlorinated hydrocarbon insecticides dieldrin and o,p'-DDT inhibit binding of 5alpha-dihydrotestosterone to specific receptor proteins in rat prostate cytosol. Dieldrin is less inhibitory than o,p'-DDT.

Citing Articles

Brief overview of selected aspects of testicular hormone action.

Bullock L Environ Health Perspect. 1981; 38:11-8.

PMID: 7238442 PMC: 1568444. DOI: 10.1289/ehp.813811.

O.p'-DDT causes growth of an androgen-dependent gland in Coturnix quail.

Adkins-Regan E, Hurvitz E Experientia. 1982; 38(9):1082-3.

PMID: 7128755 DOI: 10.1007/BF01955380.

Influence of chlorinated hydrocarbons, Hg2+ and methyl-Hg+ on steroid hormone receptors from eggshell gland mucosa of domestic fowls and ducks.

Lundholm C Arch Toxicol. 1991; 65(3):220-7.

PMID: 2053848 DOI: 10.1007/BF02307312.