Temperature and the Regulation of Enzyme Activity in Poikilotherms. Fructose Diphosphatase from Migrating Salmon

Overview

Journal Biochem J

Specialty Biochemistry

Date 1969 Dec 1

PMID 4311440

Citations 6

Authors

H W Behrisch

Affiliations

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Abstract

1. The calculated energy charge of the liver cell from migrating salmon is very low (0.464), in keeping with the extended starvation and high rates of muscular and biosynthetic activity of these organisms. 2. Affinity of fructose 1,6-diphosphatase for substrate increases with a decrease in temperature. 3. Arrhenius plots of the saturation kinetics are complex and suggest an interconversion of one or more forms of the enzyme; this interconversion is dependent on the identity of the cofactor. 4. Affinity of salmon fructose 1,6-diphosphatase for its allosteric inhibitor (AMP) is lower than in other fructose 1,6-diphosphatases and this enzyme-AMP interaction is largely insensitive to temperature. The functional significance of diminished AMP-sensitivity is that it allows normal or high fructose 1,6-diphosphatase activity during a low energy charge. 5. These findings suggest mechanisms for the maintenance of high rates of gluconeogenesis in salmon during spawning migration.

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References

ZYDOWO M, Makarewicz W, UMIASTOWSKI J, PURZYCKA J . Temperature dependence of AMP deamination catalysed by muscle extracts from homeothermic and poikilothermic animals. Acta Biochim Pol. 1965; 12(4):319-25. View

MASSEY V, Curti B, Ganther H . A temperature-dependent conformational change in D-amino acid oxidase and its effect on catalysis. J Biol Chem. 1966; 241(10):2347-57. View

HORECKER B, Pontremoli S, Rosen O, Rosen R . Structure and function in fructose diphosphatase. Fed Proc. 1966; 25(5):1521-8. View

Preiss J, Biggs M, Greenberg E . The effect of magnesium ion concentration on the pH optimum of the spinach leaf alkaline fructose diphosphatase. J Biol Chem. 1967; 242(9):2292-4. View

Atkinson D, Walton G . Adenosine triphosphate conservation in metabolic regulation. Rat liver citrate cleavage enzyme. J Biol Chem. 1967; 242(13):3239-41. View

Wallace J, Newsholme E . A comparison of the properties of fructose 1,6-diphosphatase, and the activities of other key enzymes of carbohydrate metabolism, in the livers of embryonic and adult rat, sheep and domestic fowl. Biochem J. 1967; 104(2):378-84. PMC: 1270597. DOI: 10.1042/bj1040378. View

Iwatsuki N, Okazaki R . Mechanism of regulation of deoxythymidine kinase of Escherichia coli. II. Effect of temperature on the enzyme activity and kinetics. J Mol Biol. 1967; 29(1):155-65. DOI: 10.1016/0022-2836(67)90187-8. View

Williamson J, Cheung W, Coles H, Herczeg B . Glycolytic control mechanisms. IV. Kinetics of glycolytic intermediate changes during electrical discharge and recovery in the main organ of Electrophorus electricus. J Biol Chem. 1967; 242(21):5112-8. View

Williamson J, Herczeg B, Coles H, Cheung W . Glycolytic control mechanisms. V. Kinetics of high energy phosphate intermediate changes during electrical discharge and recovery in the main organ of Electrophorus electricus. J Biol Chem. 1967; 242(21):5119-24. View

10.

Newsholme E, Gevers W . Control of glycolysis and gluconeogenesis in liver and kidney cortex. Vitam Horm. 1967; 25:1-87. DOI: 10.1016/s0083-6729(08)60033-3. View

11.

POGELL B, Tanaka A, Siddons R . Natural activators for liver fructose 1,6-diphosphatase and the reversal of adenosine 5'-monophosphate inhibition by muscle phosphofructokinase. J Biol Chem. 1968; 243(7):1356-67. View

12.

Koster J, Veeger C . The relation between temperature-inducible allosteric effects and the activation energies of amino-acid oxidases. Biochim Biophys Acta. 1968; 167(1):48-63. DOI: 10.1016/0005-2744(68)90276-3. View

13.

Somero G, Hochachka P . The effect of temperature on catalytic and regulatory functions of pyruvate kinases of the rainbow trout and the antarctic fish Trematomus bernacchii. Biochem J. 1968; 110(3):395-400. PMC: 1187363. DOI: 10.1042/bj1100395. View

14.

Hochachka P, Somero G . The adaptation of enzymes to temperature. Comp Biochem Physiol. 1968; 27(3):659-68. DOI: 10.1016/0010-406x(68)90605-1. View

15.

Behrisch H, Hochachka P . Temperature and the regulation of enzyme activity in poikilotherms. Properties of rainbow-trout fructose diphosphatase. Biochem J. 1969; 111(3):287-95. PMC: 1187510. DOI: 10.1042/bj1110287. View

16.

Somero G . Pyruvate kinase variants of the Alaskan king-crab. Evidence for a temperature-dependent interconversion between two forms having distinct and adaptive kinetic properties. Biochem J. 1969; 114(2):237-41. PMC: 1184848. DOI: 10.1042/bj1140237. View

17.

Behrisch H, Hochachka P . Temperature and the regulation of enzyme activity in poikilotherms. Properties of lungfish fructose diphosphatase. Biochem J. 1969; 112(5):601-7. PMC: 1187762. DOI: 10.1042/bj1120601. View

18.

SRERE P . Studies on purified citrate-enzymes: metabolic interpretations. Biochem Soc Symp. 1968; 27:11-21. View

19.

Atkinson D . Citrate and the citrate cycle in the regulation of energy metabolism. Biochem Soc Symp. 1968; 27:23-40. View

20.

Idler D, TSUYUKI H . Biochemical studies on sockeye salmon during spawning migration. I. Physical measurements, plasma cholesterol, and electrolyte levels. Can J Biochem Physiol. 1958; 36(8):783-91. View