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Phagocytosis of Chrysotile Fibers by Pleural Mesothelial Cells in Culture

Overview
Journal Am J Pathol
Publisher Elsevier
Specialty Pathology
Date 1979 Mar 1
PMID 426038
Citations 19
Authors
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Abstract

Pleural mesothelial cells (PMC) from the parietal pleura of rats were incubated in culture with UICC A chrysotile fibers. The sequence of events in phagocytosis was studied by electron microscopy: phases of attachment sequestration, and degranulation of lysosomal content into the phagocytic vacuole were observed. This demonstrates that PMC can engage in phagocytosis of chrysotile fibers.

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