Diminished Activity of Platelet Monoamine Oxidase in Down's Syndrome

Overview

Journal Am J Hum Genet

Publisher Cell Press

Specialty Genetics

Date 1971 Mar 1

PMID 4253914

Citations 3

Authors

P F Benson

J Southgate

Affiliations

Soon will be listed here.

Citing Articles

Aging rather than aneuploidy affects monoamine neurotransmitters in brain regions of Down syndrome mouse models.

Dekker A, Vermeiren Y, Albac C, Lana-Elola E, Watson-Scales S, Gibbins D Neurobiol Dis. 2017; 105:235-244.

PMID: 28624415 PMC: 5536154. DOI: 10.1016/j.nbd.2017.06.007.

The effect of adrenaline on human platelet MAO activity.

Gentil V, Greenwood M, Lader M Psychopharmacologia. 1975; 44(2):187-90.

PMID: 1105633 DOI: 10.1007/BF00421008.

Platelet monoamine oxidase activity in first-degree relatives of schizophrenic patients.

Propping P, Friedl W Psychopharmacology (Berl). 1979; 65(3):265-72.

PMID: 117498 DOI: 10.1007/BF00492214.

References

Rosner F, Ong B, PAINE R, MAHANAND D . Biochemical differentiation of trisomic Down's syndrome (mongolism) from that due to translocation. N Engl J Med. 1965; 273(25):1356-61. DOI: 10.1056/NEJM196512162732503. View

Doery J, Hirsh J, Garson O, de Gruchy G . Platelet-phosphohexokinase levels in Down's syndrome. Lancet. 1968; 2(7574):894-5. DOI: 10.1016/s0140-6736(68)91057-x. View

Robinson D, Lovenberg W, Keiser H, SJOERDSMA A . Effects of drugs on human blood platelet and plasma amine oxidase activity in vitro and in vivo. Biochem Pharmacol. 1968; 17(1):109-19. DOI: 10.1016/0006-2952(68)90163-9. View

SADLER J, Novick A . THE PROPERTIES OF REPRESSOR AND THE KINETICS OF ITS ACTION. J Mol Biol. 1965; 12:305-27. DOI: 10.1016/s0022-2836(65)80255-8. View

Tu J, ZELLWEGER H . Blood-serotonin deficiency in Down's syndrome. Lancet. 1965; 2(7415):715-6. DOI: 10.1016/s0140-6736(65)90454-x. View

OBrien D, GROSHEK A . The abnormality of tryptophane metabolism in children with mongolism. Arch Dis Child. 1962; 37:17-20. PMC: 2018883. DOI: 10.1136/adc.37.191.17. View

JEROME H . [Abnormalities of tryptophan metabolism in mongolism]. Bull Mem Soc Med Hop Paris. 1962; 113:168-72. View

Bertaccini G . Tissue 5-hydroxytryptamine and urinary 5-hydroxyindoleacetic acid after partial or total removal of the gastro-intestinal tract in the rat. J Physiol. 1960; 153(2):239-49. PMC: 1359746. DOI: 10.1113/jphysiol.1960.sp006532. View

VAZQUEZ H, PIAN E, HOJMAN N . [The use of nialamide in mongoloid children. (Preliminary report)]. Sem Med. 1961; 118:803-7. View

10.

Tissot R, GUGGISBERG M, Constantinidis J, BETTSCHART W . [Urinary excretion of 5-hydroxyindoleacetic acid, vanillomandelic acid and xanthurenic acid in 18 Mongoloids]. Pathol Biol. 1966; 14(5):312-6. View

11.

JEROME H, LeJeune J, TURPIN R . [Study of the urinary excretion of some tryptophan metabolites in mongoloid children]. C R Hebd Seances Acad Sci. 1960; 251:474-6. View

12.

BAZELON M, PAINE R, Coeiw V, Hunt P, Houck J, MAHANAND D . Reversal of hypotonia in infants with Down's syndrome by administration of 5-hydroxytryptophan. Lancet. 1967; 1(7500):1130-3. DOI: 10.1016/s0140-6736(67)91708-4. View

13.

Rosner F, Ong B, PAINE R, MAHANAND D . BLOOD-SEROTONIN ACTIVITY IN TRISOMIC AND TRANSLOCATION DOWN'S SYNDROME. Lancet. 1965; 1(7397):1191-3. DOI: 10.1016/s0140-6736(65)92722-4. View

14.

Krajl M . A rapid microfluorimetric determination of monoamine oxidase. Biochem Pharmacol. 1965; 14(11):1684-6. DOI: 10.1016/0006-2952(65)90025-0. View

15.

HAVERBACK B, DAVIDSON J . Serotonin and the gastrointestinal tract. Gastroenterology. 1958; 35(6):570-8. View

16.

LOWRY O, ROSEBROUGH N, FARR A, RANDALL R . Protein measurement with the Folin phenol reagent. J Biol Chem. 1951; 193(1):265-75. View