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» Articles » PMID: 4176829

Dysgammaglobulinaemia in Tropical Sprue

Overview
Journal Br Med J
Specialty General Medicine
Date 1968 Nov 16
PMID 4176829
Citations 4
Authors
S Jarnum
K N Jeejeebhoy
Affiliations
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Abstract

Study of immunoglobulin levels in 16 Indian control subjects showed that, compared with a Danish control series, they had a significantly higher mean level of IgG, but not of IgA or IgM. By contrast, the IgG levels in eight patients with tropical sprue were decreased or low normal in six cases and raised in only one case. Two patients with tropical sprue had agamma-A-globulinaemia.Turnover studies with (125)I-labelled IgG showed a high rate of synthesis in three Indian controls and an appreciably reduced or low rate in seven of the eight cases of tropical sprue.

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Immunoflobulins and malabsorption.

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